INTRANASAL VIRULENCE OF PNEUMOCOCCI FOR MICE
نویسندگان
چکیده
منابع مشابه
Intranasal Virulence of Pneumococci for Mice
1. Smooth colony pneumococci fresh from human beings, instilled in small doses into the nasal passages of special mice raised under standard conditions, brought about a characteristic infection and this spread to healthy contacts inciting in them the carrier state or fatal infection. 2. Differences in individual host response to the same dose of a given culture ranged from a complete refractory...
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Variations in the agglutinability and virulence of certain strains of pneumococci have long been noticed. Neufeld (1) reported in 1902 that a strain which had previously been agglutinated by his immune serum, after it had been grown for a long time in artificial media, failed to be agglutinated. At the same time it had become avirulent. In more recent years much work has been carried on concern...
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BACKGROUND: Influenza outbreak has become a great lifethreateningdisease in the world. Nasal vaccines can inducesystemic IgG and mucosal IgA antibody responses, whichestablish two layers of immune defense against the infectiouspathogens like influenza. Mucosal vaccines must overcomeseveral limitations, including the mucociliary clearance andinefficient uptake of soluble antigens. Therefore, nas...
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The virulence of Pasteurella multocida (P. multocida) serotype A1 for chickens and mice was determined. Groups of chicken and mice were exposed intramuscularly and intraperitoneally to various concentration of P. multocida broth culture, respectively. This strain was highly virulent for chickens so that those exposed to only 7 c.f.u. of the organism died in less than 24 hours. Groups of mice ex...
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1. When mice are passively immunized by the intraperitoneal injection of antipneumococcus horse serum or actively by the injection of heat-killed pneumococcus cultures, and are then alcoholized and sprayed with a culture of pneumococci of the same type as that of the bacteria employed in immunization, a considerable number die with localized lesions in the lungs. 2. If instead of injecting immu...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1933
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.58.4.465